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Research References on Glucosamine and MSM
(From the Manufacturer)

1.   Hayllyar J et al. Gastro protection and nonsteroidal anti-inflammatory drugs. Drug Safety, 7, 86,:86-105, 1992.
2.   Ament P W et al. Prophylaxis and treatment of NSAID-induced gastropathy. Am Fam Phys 1997. 1997;4:1323-6.
3.   Silverstein F E et al. Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis. JAMA, 284 (10): 1247-1255, 2000.
4.   Simon L S. Osteoarthritis: A Review Clinical Cornerstone. 2 (2):26-34, 1999.
5.   Pizzorno, J. Total Wellness. Prima Publishing, 1996 : 169-184
6.   Scherak, O., et al. High dosage vitamin E therapy in patients with activated arthrosis. Z-Rheumatol, 1990; Vol.46 (6) : 369-373
7.   Heinle, k., et al. Selenium concentration in erythrocytes of patients with rheymatoid arthritis. Clinical and laboratory chemistry infection markers during administration of selenium. Med-Klin, 1997; 92 (suppl), 3 : 29-31
8.   Deadhar 50 et al. Preliminary studies on anti rheumatic activity of curcumin. Ind J Med Res 1980; 71:632-34.
9.   Satoskar R R et al. Evaluation of anti-inflammatory property of curcumin in patients with post-operative inflammation. Int J Clin Pharmacal Ther Toxical 1986; 24:651-54.
10. Murray M T. The Healing Power of Herbs. Prima Publishing, Rocklin CA; 1995: 327-35.
11. Arora R B et al. Anti-inflammatory studies on curcuma longa (turmeric). Ind J Med, Res 1971; 50: 1289-95.
12. Schweizer S et al. Workup-dependent formation of 5-lipoxygenase inhibitory boswellic acids analogues. J Nat Prod 2000, Aug; 63 (8): 1058-1061.
13. Etzel R. Special extract of boswellia serrata (H15) in the treatment of rheumatoid arthritis. Phytomed 1996; 3: 91-94.
14. Bradley P R et al. British Herbal Compendium, Vol 1, Bournemouth, Dorset, UK: British Herbal Med Assoc., 1992, 224-26.
15. Mills S Y et al. Effects of a proprietary herbal medicine on the relief of chronic arthritic pain: A double-blind study. Br J Rheum 1996; 35: 874-78.
16. Chrubasik S et al. Treatment of low back pain exacerbations with willow bark extract: a randomized double – blind study. Am J Med 2000 July; 109 (1):9-14.
17. Srivastava K C et al. Ginger in rheumatism and musculoskeletal disorders. Medical Hypotheses 1992; 39:342-8.
18. Bliddal H et al. A randomized placebo – controlled, cross-over study of ginger extracts and ibuprofen in osteoarthritis. Osteoarthritis Cartilage. 2000, Jan; 8 (1): 9-12.
19. Klein G et al. Short-term treatment of painful osteoarthritis of the knee with oral enzymes. Clin Drug Invest 19 (1): 15-23, 2000.
20. Cohen A et al. Bromelain therapy in rheumatoid arthritis. Pennsyl Med J, 67: 627-30, June 1964.
21. Seligman B. Bromelain: An anti-inflammatory agent. Angiology, 13: 508-510, 1962.
22. Ferrandiz J L et al. Anti-inflammatory activity and inhibition of arachidonicacid metabolism by flavonoids. Agents Action; 32: 283-287, 1991.
23. Tarayre J P et al. Advantages of a combination of proteolytic enzymes, flavonoids and ascorbic acid in comparison with nonsteroidal anti-inflammatory agents. Arzneium forsch, 27:1144-1149, 1977.
24. Yoshimoto T et al. Flavonoids and potent inhibitors of arachidonate 5 – lipoxygenase. Biochem Biophys Res Comm., 116: 612-18, 1983.
25. Weiss R F. Herbal Medicine. Beaconsfield : Beaconsfield Press, 1988; p.362
26. Grahame R et al. Devil’s Claw: Pharmacological and clinical studies. Ann Rheum Dis, 1 981; 40: 632.
27. Gottleib M.S. Conservative management of spinal osteoarthritis with glucosamine sulfate and chiropractic treatments. J. Manipulative Physiol Ther. 1997 July – Aug; 20 (6): 400-414. (JMPT)
28. McAlindon, T.E., et al. Glucosamine and chondroitin for treatment of osteoarthritis: a systematic quality assessment and meta-analysis. JAMA, 2000; 283,11: 1469-1475
29. Reginster, J.Y., et al. Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomized, placebo-controlled clinical trial. Lancet, 2000; 357, 9252: 251-256
30. Murray, M. Glucosamine Sulfate: Nature’s arthritis cure. The Chiropractic Journal – March, 1998
31. Richmond, V.L. Incorporation of methylsulfonylmethane sulfur into guinea pig serum proteins. Life Sci, 1986; 39: 263-268
32. Sullivan, M.W., et al. The cystine content of the finger nails in arthritis. J Bone Joint Surgery, 1935; 16: 185-188
33. Lawrence, R.M. Methylsulfonylmethane (MSM): A double-blind study of its use in degenerative arthritis. Int J Anti-Aging Medicine, 1998; 1, 1: 50